Searchable abstracts of presentations at key conferences in endocrinology

ea0067o6 | Oral Presentations | EYES2019

Local hypothyroidism in brain cortex leads to diminished glucose metabolism in Alzheimer’s disease animal model

Shcholok Tetiana , Gorbach Tetiana

Objective: This study analyzes impairments occurred in local thyroid hormones metabolism and their connection to decreased glucose uptake, amyloid-β accumulation and apoptosis of neurons in pharmacologically induced animal model of Alzheimer’s disease.Methods: Spectrophotometry, immunoassay, morphological studies including immunohistochemistry, rat Scopolamine-induced Alzheimer’s disease model (WAG male rats).Results...